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Increasing the effectiveness
of adherence interventions
may have a far greater impact
on the health of the population
than any improvement in
specific medical treat-
ments." Haynes RB.
Interventions for helping
patients to follow prescriptions
for medications. Cochrane
Database of Systematic Reviews, 2001,
Issue 1. |
Patient Adherence, Compliance and Persistency Facts
There is an increasing mountain of evidence regarding the cost and impact of patient non-adherence and compliance and persistency with prescribed medication treatments.
- Chronic medication compliance has been estimated at only 50% in two different studies. 2
- Fewer than one in three patients are adherent with combined anti-hypertensive and lipid-lowering therapy at six months. 3
- The longer a patient is on a drug, the more likely they are to start skipping doses. 1
- Estimates for prescriptions that are never filled vary from 20-33%, with estimates for refills never filled even higher (30-40%).
- The cost of noncompliance has been estimated in the billions for all stakeholders- employers, the healthcare system, pharmacies, insurance companies, hospitals, and pharmaceutical manufacturers.
- The cost of noncompliance for the average pharmaceutical brand is 38% of its sales, and $30 billion in lost revenue for the industry4, with an additional $8 billion annual revenue loss for pharmacies in unfilled prescriptions. 5
- The FDA estimates that 90 million Americans have low health literacy, meaning they dont understand their condition or treatment regimen.
- The June, 2007 Guideline Trend Report published in MedAd News estimates lost annual revenue in the statin category at $4 billion dollars annually.
Even incremental gains in compliance can reap big rewards for a product line in sales, generate a positive ROI, and help break through the barriers of patient compliance.
See the benefits of a PharmaPhoneticstm Patient Adherence program, visit our product overview to learn more about our Patient Adherence programs. Contact us, or telephone us at 585-248-9289 for additional details.
1 NCPIE, Enhancing Prescription Medicine Adherence: A National Action Plan, 2007
2 Haynes RB, Interventions for helping patients to follow prescriptions for medications: Cochrane Database of Systematic Review, 2001 Issue I, and 1.
3 Chapman, RH Benner, J.S. Petrilla, A.A. Tierce, J.C. Collins, S.R. Battleman, D.S. Schwartz, J.S. (2005) Predictors of Adherence With Antihypertensive and Lipid-Lowering Therapy. Arch Intern Med 165: 1147-1152
4 Cutting Edge Information. Pharmaceutical Patient Adherence and Disease Management: Program development, Management and Improvement
5 Jackson RA, Worthen DB, Barret CW. The financial aspects of improved refill management. Practice Opportunities. Cinncincati, Ohio: Proctor & Gamble Health Care; 1998:1-15. |
